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Figure 5 | Journal of Translational Medicine

Figure 5

From: A small molecule activator of AKT does not reduce ischemic injury of the rat heart

Figure 5

Ischemic injury. A: Abundance of creatine kinase in the perfusion buffer at reperfusion. B: Activity of lactate dehydrogenase (LDH) in the perfusion buffer at reperfusion. C: Infarct size as measured by histology after staining with Triphenyltetrazolium chloride. D: Representative histological sections of the left ventricle; Each dot within the bars represents one animal of the group. Note that IR-Low-Post shows 10 animals in panels “A” and “B” because one rat was detected as an outlier for these measurements. Other groups show data from all 11 animals. Data are shown as mean ± SE. &, p < 0.05 all other groups.

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