miR-130a can predict response to temozolomide in patients with glioblastoma multiforme, independently of O6-methylguanine-DNA methyltransferase

Table 2 Cox regression analyses of the associations of miR-130a and clinical characteristics with OS in TCGA

Variable	Univariate Cox regression			Multivariate Cox regression
	Hazard ratio	95% CI	*p value*	Hazard ratio	95% CI	*p value*
Gender	0.776	0.536–1.125	0.181
Age	1.027	1.012–1.042	0.001	1.016	0.998–1.035	0.088
MGMT methylation	0.559	0.361–0.864	0.009	0.654	0.413–1.008	0.054
miR-130a	0.558	0.426–0.733	0.000	0.665	0.473–0.935	0.019

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