Table 1 Physiological characteristics of GIPR dn transgenic pigs one week prior to the start of liraglutide/placebo treatment
Parameter | Control group | Treatment group | P |
|---|---|---|---|
(Placebo) | (Liraglutide) | ||
n = 9 | n = 9 | ||
4 m, 5 f | 4 m, 5 f | ||
Age [days] | 60 ± 0.14 | 60 ± 0.14 | 1.00 |
Body weight [kg] | 15 ± 1.00 | 16 ± 0.73 | 0.41 |
MMGTT | |||
AUC glucose | 17839 ± 682 | 18375 ± 881 | 0.80 |
AUC insulin | 2956 ± 187 | 3296 ± 261 | 0.30 |
IVGTT | |||
AUC glucose | 13015 ± 592 | 12821 ± 458 | 0.86 |
AUC insulin | 719 ± 69 | 862 ± 75 | 0.08 |