Figure 2
Body weight gain and food intake in liraglutide- and placebo-treated GIPR dn transgenic pigs. (A) Body weight gain of GIPRdn transgenic pigs during pre-treatment and treatment period, black arrows indicate beginning/end of liraglutide/placebo administration. (B) Representative physical appearance of two female littermates (L = liraglutide-treated pig, P = placebo-treated pig) during the last third of the treatment period. (C) Food intake and (D) feeding efficiency of liraglutide- vs. placebo-treated GIPRdn transgenic pigs during the treatment period, n = number of animals investigated. Data are means ± SEM. For statistical analysis (ANOVA; Linear Mixed Models; SAS 8.2), data were square-root transformed. *: p < 0.05, **: p < 0.01, ***: p < 0.001.