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Table 1 Patients information used in the whole study

From: Inherent transcriptional signatures of NK cells are associated with response to IFNα + rivabirin therapy in patients with Hepatitis C Virus

 

Training group

Validating group

Healthy donors

Reverse validating group

Total patients

HCV Treatment Response

5 NR

4 SVR

5 NR

5 SVR

NA

NA

n=19

Caucasian

n=5

n=4

n=5

n=5

n=7

n=8

n=34

HCV genotype 1

n=5

n=4

n=5

n=5

NA

n=8

n=28

HCV Treatment naïve

n=5

n=4

n=5

n=5

n=7

n=8

n=34

Age mean±SD

44,2±18,36

32,3±14,43

60±7,8

51±6,4

45±4

48±16

n=34

Viral Load mean ±SD

3256750 ± 2672345,209

646000 ± 234921,3

3076667 ± 2438080

1506000 ± 1887003

NA

1908796 ± 1457469

n=27

ALT mean±SD

90,25±41,83

48±7

66 ± 55

116±90,23

NA

72±65

n=27

F1

n=2

n=2

n=0

n=2

NA

n=2

n=8

F2

n=0

n=1

n=0

n=1

NA

n=2

n=4

F3

n=0

n=1

n=3

n=1

NA

n=3

n=9

F4

n=3

n=0

n=2

n=1

NA

n=3

n=9

Total patients

n=9

n=10

n=7

n=8

n=34

  1. Legend: NR = Non responders; SVR=sustained virologic responders; HD=Healthy donors. SD= Standard Deviation. Viral Load values are expressed as viral copies (CP)/ml; ALT values are expressed as UI/ml. Fibrosis in patients with HCV was staged according to the Metavir classification, which ranges from F0 to F4 (F0 = no fibrosis; F1 = portal fibrosis without septa; F2 = portal fibrosis with few septa; F3 = portal fibrosis with many septa; and F4 = cirrhosis).