Skip to main content

Table 1 Comparison of baseline characteristics of patients with symptomatic calcified aortic stenosis and without (Group A) or with (Group B) concomitant coronary atherosclerosis

From: Serum Dickkopf-1 signaling and calcium deposition in aortic valve are significantly related to the presence of concomitant coronary atherosclerosis in patients with symptomatic calcified aortic stenosis

 

Group A

Group B

P-value

N = 112

N = 106

Age years, mean (SD)

69.7 (11.5)

75.7 (8.7)

<0.001

Men N (%)

60 (53.6)

63 (59.4)

0.657

Obesity N (%)

43 (38.7)

34 (32.4)

0.633

Hyperlipidemia N (%)

37 (33.0)

38 (35.9)

0.892

Hypertension N (%)

70 (62.5)

83 (78.3)

0.024

Diabetes mellitus N (%)

33 (29.5)

43 (40.6)

0.172

Smoking (anytime) N (%)

26 (23.4)

41 (39.4)

0.081

IACE therapy N (%)

42 (37.5)

43 (41.0)

0.895

ARB therapy N (%)

12 (10.71)

20 (19.05)

0.170

Statin therapy N (%)

33 (23.7)

51 (48.6)

0.011

Pressure gradient across the aortic valve (mmHg);

   

  Mean ± SD

44.4 ± 17.9

40.4 ± 15.5

0.128

  Median (25th to 75th percentile)

43 (32 to 57)

41 (28 to 50)

 

Peak aortic valve velocity (m/s)

   

  Mean ± SD

4.1 ± 0.8

4.0 ± 0.8

0.107

  Median (25th to 75th percentile)

4.2 (3.6 to 4.7)

4.0 (3.4 to 4.4)

 

Severe aortic stenosis N (%)

100 (89.3)

85 (18.2)

0.088

  1. SD – standard deviation; IACE – inhibitors of ACE; ARB – angiotensin II receptor blockers.