Figure 4

Ability of STC1 in influencing the migration and invasion of ccRCC cells in vitro . (A) (B) Representative photographs of Transwell assays (magnification, ×100) in Caki-1 and A498 cells. (C) (D) Confluent monolayer cells were scratched using a sterile 200 μL pipette. Photos of the wound were taken at different time points (0, 12, and 24 h after scratching). STC1 knockdown impaired the cell mobility in Caki-1 and A498 cells. Each experiment was performed triplicates. *,P < 0.05; **,P < 0.01.