Performance of a multiplexed dual analyte immunoassay for the early detection of non-small cell lung cancer

Table 2 ROC curve area comparison

*A. From a logistic regression analysis*
Biomarker	Transformation	AUC ^a	Standard error	95% Wald Confidence Limits		Probability ^b
Biomarker	Transformation	AUC ^a	Standard error	Lower	Upper	Probability ^b
NY-ESO-1	Raw	0.60	0.04	0.52	0.67	0.0102
CEA	Raw	0.79	0.03	0.74	0.85	<0.0001
CA125	Raw	0.70	0.03	0.63	0.77	<0.0001
CYFRA 21-1	Raw	0.69	0.04	0.62	0.76	<0.0001
4 Biomarker Model^c	Raw	0.83	0.03	0.78	0.88	<0.0001
*B. From a MoM analysis*
Biomarker	Transformation	AUC ^a	Standard error	95% Confidence Interval		Probability ^b
Biomarker	Transformation	AUC ^a	Standard error	Lower	Upper	Probability ^b
NY-ESO-1	Raw	0.60	0.04	0.52	0.67	0.01007
CEA	Raw	0.79	0.03	0.74	0.85	<0.0001
CA125	Raw	0.70	0.03	0.63	0.77	<0.0001
CYFRA 21-1	Raw	0.69	0.04	0.62	0.76	<0.0001
4 Biomarker Model^c	Raw	0.81	0.03	0.75	0.86	<0.0001

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