Skip to main content

Table 3 Oxidative stress markers of the study groups (mean ± SD)

From: Rosuvastatin attenuates contrast-induced nephropathy through modulation of nitric oxide, inflammatory responses, oxidative stress and apoptosis in diabetic male rats

 

NDCM (n = 8)

D (n = 8)

DR (n = 8)

DCM (n = 8)

DRCM (n = 8)

Kidney TBARS (nmol/g)

36.21 ± 5.21#

30.23 ± 6.30

29.38 ± 5.38

42.62 ± 6.12*

32.26 ± 4.28

Serum MDA (μmol/l)

7.23 ± 1.12#

3.03 ± 0.52

3.18 ± 0.61

9.25 ± 1.23*

4.56 ± 0.78+

Serum Thiol (μmol/l)

287.78 ± 29.23#

362.25 ± 58.16

343.16 ± 62.11

247.16 ± 23.87*

346.19 ± 30.18**

Serum PCC (μmol/l)

10.11 ± 1.34#

7.68 ± 1.21

8.12 ± 0.92

14.23 ± 1.73*

8.38 ± 1.19**

  1. NDCM: non-diabetic rats + contrast media, D: diabetic group, DCM: diabetic rats + contrast media, DR: diabetic rats + rosuvastatin, DRCM: diabetic rats + rosuvastatin + contrast media.
  2. *P < 0.01 vs NDCM, D, DR and DRCM; + P < 0.05 vs NDCM, D and DR; # P < 0.05 vs D, DR; **P < 0.05 vs NDCM.