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Figure 5 | Journal of Translational Medicine

Figure 5

From: A chimeric EBV gp350/220-based VLP replicates the virion B-cell attachment mechanism and elicits long-lasting neutralizing antibodies in mice

Figure 5

Comparative analysis of IgG subclass responses to vaccination with EBVgp350/220 containing immunogens: EBVgp350/220-F VLPs, UV-EBV and soluble recombinant gp350/220 ED. Serum IgG subclass titers were determined on days 14, 56, 154 and 228 post-vaccination by gp350/220 ED-based ELISA. Immunizations were carried out as described in FigureĀ 4. TNE was the vehicle control. X-axis displays immunogen and date of vaccination. Y-axis indicates antibody titer specific for soluble recombinant gp350/320 ED on a log scale (A) IgG1 (B) IgG2a (C) IgG2b (D) IgG3.

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