Table 4 Precision of GFR measurements and time to steady state during CILDI
Method B Precision (Plasma clearance) | ||||
|---|---|---|---|---|
Subject | 95% CI | 99% CI | 3 SD^ | Time to steady state (min) [no. samples] |
Healthy Volunteers | ||||
1 | 2.9 | 3.9 | 4.5 | 98 [7] |
2 | 10.4 | 13.6 | 15.9 | 248 [4] |
3 | 2.7 | 3.6 | 4.2 | 126 [6] |
4 | 8.3 | 10.8 | 12.7 | 287 [4] |
5 | 1.3 | 1.7 | 2.0 | 118 [7] |
6 | 3.1 | 4.0 | 4.7 | 127 [6] |
7 | 4.5 | 6.0 | 6.9 | 86 [8] |
8 | 3.5 | 4.7 | 5.4 | 205 [5] |
9 | 4.7 | 6.2 | 7.2 | 110 [7] |
10 | 5.8 | 7.6 | 8.9 | 154 [6] |
11 | 1.0 | 1.4 | 1.6 | 143 [6] |
Mean ± SD | 4.4 ± 2.9 | 5.8 ± 3.7 | 6.7 ± 4.4 | 155 ± 126 |
Chronic Kidney Disease | ||||
12 | 6.6 | 8.7 | 10.2 | 555 [3*] |
13 | 17.7 | 23.2 | 27.1 | 598 [3*] |
14 | 15.8 | 20.8 | 24.2 | 508 [3*] |
15 | 6.3 | 8.3 | 9.6 | 327 [4] |
16 | 6.9 | 9.1 | 10.6 | 335 [3] |
17 | 12.5 | 16.3 | 19.1 | 600 [3*] |
Mean ± SD | 11.0 ± 5.1 | 14.4 ± 6.6 | 16.8 ± 7.4 | 487 ± 65 |
All Volunteers | ||||
Mean ± SD | 6.7 ± 4.9 | 8.8 ± 6.4 | 10.3 ± 7.4 | 172 ± 185 |