Effect of CLE on hepatic glycogen and mRNA expression of hepatic glucose-regulating enzymes in db/db mice. Following an overnight fasting, mice were sacrificed and the hepatic tissues were collected for hepatic glycogen determination, and mRNA expression analysis of hepatic glucose regulating enzymes. A) Hepatic glycogen; B) mRNA expression. Each value represents the mean ± SE, n = 7 mice. ##
p < 0.01, control group versus normal group; *
p < 0.05 and **
p < 0.01, control group versus sample treated groups.