Effect of CLE on insulin-signaling molecules’ expression in the skeletal muscles of db/db mice. Following an overnight fasting, mice were sacrificed and the skeletal muscle tissues were collected for mRNA or protein expression of insulin signaling molecules using RT-PCR or Western blot, respectively. A) Protein expression; B) mRNA expression. Each value represents the mean ± SE, n = 7 mice. ##
p < 0.01, control group versus normal group; *
p < 0.05 and **
p < 0.01, control group versus sample treated groups.