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Table 1 Correlations between the proportion of circulating MDSCs and the clinical characteristics of CRC patients

From: Tumor-induced myeloid-derived suppressor cells promote tumor progression through oxidative metabolism in human colorectal cancer

Characteristics No. of patients Mean of circulating MDSCs P value
   Low (≤4.0%) a High (>4.0%) a  
Age (years)     
≤60 27 16 11  
>60 15 11 4 0.506
Gender     
Male 20 12 8  
Female 22 15 7 0.749
TNM stage     
I-II 24 19 5  
III-IV 18 8 10 0.020*
T stage     
T2 3 1 2  
T3 28 20 8  
T4 11 6 5 0.312 (Fisher’s)
Tumor size (cm)     
≤5 25 15 10  
>5 17 12 5 0.531
Lymph node metastasis     
No 26 21 5  
Yes 16 6 10 0.008**
Histological grade     
Well/moderate 24 18 6  
Poor/undifferentiated 18 9 9 0.116
Venous invasion     
No 38 26 12  
Yes 4 1 3 0.122
Serum CEA (ng/mL)     
≤5 22 16 6  
>5 20 11 9 0.336
  1. Note: a4.0% indicates the mean percentage of circulating MDSC; *indicates P < 0.05; **indicates P < 0.01; determined by Pearson χ 2 test and Fisher’s exact test.