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Figure 3 | Journal of Translational Medicine

Figure 3

From: Tumor-induced myeloid-derived suppressor cells promote tumor progression through oxidative metabolism in human colorectal cancer

Figure 3

Decreased proportions of circulating HLA-DR CD33 + CD11b + MDSCs and CD4 + CD25 high FOXP3 + Treg cells in CRC patients after tumor resection. PBMCs were isolated from 26 CRC patients before and after surgery. (A-D) Representative density plots of circulating HLA-DRCD33+CD11b+ MDSCs, CD4+CD25highFOXP3+ Tregs, CD3+CD4+ T cells, CD3+CD8+ T cells, and CD3CD16+ NK cells from one CRC patient before and after surgery are shown. (E-H) The graph shows that the proportions of circulating MDSCs and Tregs were significantly decreased after surgery (P < 0.05), whereas the proportions of CD3+CD4+ T cells, CD3+CD8+T cells, and CD3CD16+ NK cells were not significantly different after the operation (P > 0.05).

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