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Table 2 Estimates of the parameters of the final model and results of Bootstrap analyses

From: Pharmacokinetic model of unfractionated heparin during and after cardiopulmonary bypass in cardiac surgery

Parameter

Final model estimate (RSE%)

Bootstrap median

Bootstrap CI (95%)

CLUFH, 1-order (L·h–1)

1.18 (7.25)

1.18

0.99, 1.35

VUFH-C (L)

3.04 (8.09)

3.02

2.57, 3.51

QUFH (L·h–1)

0.171 (14.40)

0.160

0.0977, 0.311

VUFH-P (L)

8.01 (31.8)

7.01

2.63, 27.6

ω2 CL(UFH, 1-order)

0.122 (77.7)

0.126

0.00452, 0.310

ω2 V(UFH-C)

0.105 (48.7)

0.0966

0.0239, 0.197

ω2 Q(UFH)

0.0978 (76.9)

0.105

0.00498, 0.259

ω2 V(UFH-P)

0 (FIX)

0 (FIX)

0 (FIX)

σ2 pro(UFH)

0.139 (14.2)

0.135

0.105, 0.167

σ2 add(UFH)

0 (FIX)

0 (FIX)

0 (FIX)