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Table 2 Frequencies of somatic mutations in the three candidate genes

From: Activating PIK3CA mutations coexist with BRAF or NRAS mutations in a limited fraction of melanomas

Sample

BRAF

NRAS

BRAF + PIK3CA

NRAS + PIK3CA

PIK3CA

Wild-type

%

%

%

%

%

%

Primary melanoma (N = 212)

81

21

9

1

10

90

38.2

9.9

4.2

0.5

4.7

42.5

Melanoma cell line (N = 33)

18

4

2

0

2

7

54.5

12.1

6.1

0

6.1

21.2

Total (N = 245)

99

25

11

1

12

97

40.4

10.2

4.5

0.4

4.9

39.6