Figure 3
Time course of leukocyte subpopulations in metastatic NSCLC patients treated with NHS-IL2 (by dose group). Absolute counts (109 cells/mm3) are shown for total leukocytes, lymphocytes, neutrophils, monocytes, basophils, and eosinophils from NSCLC patients treated with NHS-IL2 at dose levels 0.15 mg/kg, 0.30 mg/kg, and 0.45 mg/kg. Geometric mean values of absolute counts are shown for each dose level. Blood was drawn 7 days before start of treatment and at days 1 and 8 of each cycle until discontinuation. The arrow identifies the first of the 3 consecutive days of NHS-IL2 infusion. NSCLC, non-small cell lung cancer.