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Table 3 Correlation between IL-37 levels and pro-inflammatory cytokines as well as AS laboratory values

From: Interleukin-37 is increased in ankylosing spondylitis patients and associated with disease activity

Parameter

Correlation coefficient (r)

P-value

TNF-α

0.3907

0.0073

IL-6

0.4005

0.0058

IL-17

0.4922

0.0005

IL-23

0.1095

0.4689

BASADI

0.4302

0.0028

CRP

0.3208

0.0298

ESR

0.4649

0.0011

ALT

−0.2397

0.1086

PLT

0.2596

0.0815

RBC

0.04482

0.7674

  1. BASDAI, Bath ankylosing spondylitis disease activity index; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; ALT, alanine aminotransferase; PLT, Platelet; RBC, red blood cell. The correlations were evaluated with Spearman’s non-parametric test. P < 0.05 represents a significant difference.