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Table 5 Distribution of HTI-specific responses and number of mice with responses to each protein subunit

From: A human immune data-informed vaccine concept elicits strong and broad T-cell specificities associated with HIV-1 control in mice and macaques

   

Number of animals with positive response (n = 5)

HTI segments

HIV-1 protein

HTI pool (#peptides/pool)

DNA.COMB

DNA.HTI

S1a

Gag-p17

Pool1 (10)

0

2

S2

Gag-p24

Pool2 (12)

5

5

S3

Gag-p24

   

S4

Gag-p24

   

S5

Gag-p24

   

S6

Gag-p24

   

S7

Gag-p15

Pool3 (3)

0

0

S8a

Prt

Pool4 (6)

2

5

S9a

RT

Pool5 (11)

2

4

S10a

RT

   

S11

RT

   

S12

Int

Pool6 (4)

0

0

S13

Int

   

S14

Vif

Pool7 (4)

2

2

S15

Vif

   

S16a

Nef

Pool8 (2)

0

1

  1. asegments with increase in HTI-specific responses in DNA.HTI and DNA.COMB.