Breadth of HTI-specific T cell responses in vaccinated macaques. Mapping of HTI-specific T cell responses after the 3rd DNA prime and 1st and 2nd MVA boost using peptide pools covering each segment (S1-S16). The percentage of IFN-γ+ CD4+ (open bars) and CD8+ (filled bars) T cells specific for each segment is shown. For a summary of data see Table 7. Asterisk denotes new responses emerging after MVA boost vaccination.