Figure 4
Effect of barasertib-HQPA and vemurafenib on apoptosis and necrosis. Melanoma cells were treated with 30 and 300 nM barasertib-HQPA (Bar) and vemurafenib (Vem) at IC50s. (A) Apoptosis was determined by Cell Death ELISA assay and (B) Necrosis by LDH activity determination and expressed as percentage respect to the untreated cells. *p < 0.05 vs untreated cells.