Clinical significance of plasmacytoid dendritic cells and myeloid-derived suppressor cells in melanoma

Table 4 Combined Cox (upper part) and logistic (lower part) regression models comparing circulating myeloid-derived suppressor cells and plasmacytoid dendritic cells in melanoma patients

Combined Cox regression model: pDC vs MDSC & overall survival
	Coefficient	P-value	HR	95% Confidence Interval for HR
	Coefficient	P-value	HR	Lower	Upper
Stage at inclusion	1.87	<0.001	6.46	2.39	17.46
MDSC frequency	−1.61	0.009	4.98	1.50	16.67
pDC frequency	1.49	0.019	4.42	1.27	15.33
Logistic regression model: pDC and MDSC & systemic disease
	Coefficient	P-Value	OR	95% Confidence Interval for OR
	Coefficient	P-Value	OR	Lower	Upper
Stage at diagnosis	−0.702	0.407	0.496	0.095	2.601
MDSC frequency	−0.248	0.753	0.78	0.167	3.655
pDC frequency	1.741	0.032	5.705	1.159	28.091

pDC, plasmacytoid dendritic cell; MDSC, myeloid-derived suppressor cell; HR, hazard ratio; OR, odds ratio.

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