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Figure 3 | Journal of Translational Medicine

Figure 3

From: The number of circulating monocytes as biomarkers of the clinical response to methotrexate in untreated patients with rheumatoid arthritis

Figure 3

Receiver-operating characteristic ( ROC ) analysis of the absolute numbers of circulating monocytes and of their subset cells. Receiver-operating characteristic (ROC) analysis of the absolute numbers of circulating monocytes, and of the numbers of CD14+highCD16, CD14+highCD16+ and CD14+lowCD16+ subset cells (A, B, C and D, respectively). The predictive value of the absolute numbers of monocytes was determined by calculating the area under the curve (AUC). The optimum cut-offs (cells/μl) for distinguishing between MTX responders and non-responders, plus their sensitivity (Sens), specificity (Spec) values, are shown next to the curves. These were used to verify the validation of the ROC curves and to establish the predictive power of the cut-offs.

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