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Table 1 Inclusion and exclusion criteria

From: Human neural stem cell transplantation in ALS: initial results from a phase I trial

Inclusion Criteria Exclusion Criteria
Age 20 to 75 years Psychiatric disease or other neurological disease different from ALS
Non ambulatory (walking subscore 0–1 of the ALS-FRS-R scale) Evidence of any concurrent illness
Evidence of progression disease in the last six months Patients receiving corticosteroids, immunoglobulin or immunosuppressive treatment**
Absence of sleep apneas or hypopneas with blood oxygen saturation lower than 90%,* Mental deterioration or cognitive sphere disturbance
FVC higher than 60% Non-invasive ventilation (NIV) >6 hours daily Patients unable to understand informed consent form and study aims
Supposed good adherence to study protocol Women who were pregnant or childbearing potential for the duration of the study.
Good acceptance and understanding of the informed consent  
  1. *nocturnal respiratory monitoring by polysomnography.
  2. **We excluded patients who received these treatments in the 6 months prior to the transplant.