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Table 3 Cox regression analyses

From: Prognostic significance of cytoplasmic S100A2 overexpression in oral cancer patients

Predictors Test set (n = 162) Internal validation of test set* External validation set (n = 102)
HR [95% CI] p c-statistic HR [95% CI] p c-statistic HR [95% CI] p c-statistic
Univariate analyses
Cyto S100A2 % Pos 1.35 [1.09, 1.67] <0.01 0.59 1.35 [1.10, 1.76] 0.01 0.59 1.40 [1.04, 1.90] 0.03 0.60
Multivariable analyses adjusted for clinical parameters
Cyto S100A2 % Pos 1.33 [1.07, 1.65] 0.01 0.62 1.34 [1.08, 1.78] 0.03 0.59 1.47 [1.07, 2.03] 0.02 0.67
Histology grade 1.32 [0.91, 1.91] 0.14 1.32 [0.90, 1.92] 0.14 1.03 [0.65, 1.64] 0.90
Clinical stage 1.06 [0.60, 1.89] 0.83 1.07 [0.59, 1.93] 0.84 1.00 [0.65, 1.54] 0.99
Nodal status 1.30 [0.68, 2.51] 0.43 1.33 [0.69, 2.82] 0.45 2.09 [0.89, 4.92] 0.09
Tumor stage 1.10 [0.72, 1.70] 0.65 1.11 [0.71, 1.77] 0.67 1.23 [0.86, 1.78] 0.25
  1. *Internal validations were based on 9999 bootstrap samples; Optimism corrected c-statistic.