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Table 2 Variable selection using nested LRT in Test set

From: Prognostic significance of cytoplasmic S100A2 overexpression in oral cancer patients

Fitted Cox models

p*

Nuclear vs. Cytoplasmic S100A2 attributes

Nuclear variables

0.70

Cytoplasmic variables

<0.01

Combined nuclear and cytoplasmic variables

0.04

Nested LRT

0.34

Most predictive subcellular variables

Cytoplasmic S100A2

% Positivity alone vs. % Positivity & Intensity

Cytoplasmic variables

<0.01

Without cytoplasmic intensity

<0.01

Nested LRT

0.07

Most predictive variable

cytoplasmic % positivity

  1. *p corresponds to the LRT of the model fit, unless stated otherwise.