Figure 3

Time-dependent AUC plots of cytoplasmic S100A2 in OSCC and evaluation of S100A2 overexpression as a prognostic marker of OSCC. Time-dependent AUC plots for a baseline model (clinical parameters alone), a univariate model (cytoplasmic S100A2 % positivity) and an extended baseline model (clinical parameters + cytoplasmic S100A2 % positivity) in a. Test set and b. Validation set. c. Survival curves of the high risk and low risk groups in the Test set. Median survival times (months): High risk group - 16 (95% CI = 8.00, 40); Low risk group - 69 (95% CI = 14, −--). b. Survival curves of the high risk and low risk groups in the validation set. Median survival times (months): High risk group - 9.4 (95% CI = 7.00, 38.1); Low risk group - 59.9 (95% CI = 21, −--).