Abroma augusta L. (Malvaceae) leaf extract attenuates diabetes induced nephropathy and cardiomyopathy via inhibition of oxidative stress and inflammatory response

Table 3 Effect of AA on body weight and organ weight of T2D rats

Groups	Total body weight (g)	Kidney weight (g)	Heart weight (g)
Gr I	216.67 ± 7.15	0.95 ± 0.05	0.47 ± 0.03
Gr II	171.67 ± 5.58^#	1.41 ± 0.08^#	0.52 ± 0.03
Gr III	188.33 ± 6.91	1.17 ± 0.06	0.53 ± 0.04
Gr IV	192.50 ± 5.44	1.12 ± 0.09*	0.52 ± 0.04
Gr V	200.83 ± 8.60*	1.02 ± 0.06**	0.51 ± 0.02

Data were expressed as mean ± SE (n = 6). ^# p < 0.01 compared with normal control group. *p < 0.05 compared with diabetic control group. **p < 0.01 compared with diabetic control group. Gr I: Normal; Gr I: Normal; Gr II: T2D control, Gr III: T2D + AA (100 mg/kg, p.o.); Gr IV: T2D + AA (200 mg/kg, p.o.); Gr V: T2D + glibenclamide (1 mg/kg, p.o.).

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