Abroma augusta L. (Malvaceae) leaf extract attenuates diabetes induced nephropathy and cardiomyopathy via inhibition of oxidative stress and inflammatory response

Table 1 Effect of AA on fasting blood glucose level of T2D rats

Groups	Fasting blood glucose level (mg dl ⁻¹ ) in days
Groups	0	1	3	7	14	21	28
Gr I	76.48 ± 3.74	76.04 ± 4.08	76.21 ± 3.99	75.84 ± 3.62	75.63 ± 2.63	77.22 ± 2.87	76.43 ± 3.12
Gr II	171.90 ± 6.99^#	172.28 ± 6.91^#	177.44 ± 7.45	180.77 ± 6.82^#	184.13 ± 7.26^#	187.15 ± 6.15^#	190.47 ± 6.03^#
Gr III	170.63 ± 9.02^#	168.08 ± 8.76^#	146.33 ± 9.77*	142.64 ± 9.38**	138.88 ± 4.08**	133.27 ± 3.04**	129.10 ± 3.39**
Gr IV	173.22 ± 5.46^#	165.67 ± 7.39^#	142.40 ± 5.64**	136.08 ± 6.56**	126.64 ± 4.82**	121.47 ± 5.27**	113.39 ± 4.70**
Gr V	175.32 ± 7.94^#	168.88 ± 8.85^#	138.84 ± 5.59**	125.71 ± 5.75**	113.16 ± 4.49**	108.45 ± 3.73**	98.40 ± 2.83**

Data were expressed as mean ± SE (n = 6). ^# p < 0.01 compared with normal control group. *p < 0.05 compared with diabetic control group.
**p < 0.01 compared with diabetic control group. Gr I: Normal; Gr I: Normal; Gr II: T2D control, Gr III: T2D + AA (100 mg/kg, p.o.); Gr IV: T2D + AA (200 mg/kg, p.o.); Gr V: T2D + glibenclamide (1 mg/kg, p.o.).

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