Figure 4

Western blot analysis of caspase 3 (A, B, C, D), caspase 9 (E, F, G, H), Bcl-2/Bax (I, J, K, L) in the renal (A, B, E, F, I, J) and cardiac (C, D, G, H, K, L) tissues of type 2 diabetic rats and AA treated animals. The relative intensities of bands were determined and the control band was given an arbitrary value of 1. β-actin was used as a loading protein. Data were expressed as mean ± SE (n = 6). ^#p < 0.01 compared with normal control group. *p < 0.05 compared with diabetic control group. **p < 0.01 compared with diabetic control group. Gr I: Normal; Gr II: T2D control, Gr III: T2D + AA (100 mg/kg, p.o.); Gr IV: T2D + AA (200 mg/kg, p.o.); Gr V: T2D + glibenclamide (1 mg/kg, p.o.).