A developmental scheme for human DC lineages. Both cDCs and pDCs can originate from CMP and CLP lineages. Human cDCs are categorized as two main subsets including BDCA1+DCs and BDCA3+DCs. Abbreviations: HSC, hemopoietic stem cell; MPP, multipotent progenitors; CMP, common myeloid precursors; CLP, common lymphoid precursors. cDCs, conventional DCs; pDCs, plasmacytoid DCs.