Figure 1
From: Response of recurrent BRAFV600E mutated ganglioglioma to Vemurafenib as single agent
Serial MRI features of the lesion. Sagittal T2 weighted images show, at onset, a bulky mass extending from medulla into cervical spinal cord, dislocating the pons, the floor of the IV ventricle, the cerebellar vermis and tonsils (A); increased size of both cystic and solid component of the lesion after surgical decompression and chemotherapy (B); a new disease progression three months after second surgery (C); further increase of cystic components (D); a relevant reduction in size of both the solid and the cystic components of the lesion six months after the start of treatment (E).