Figure 1From: Pre-immature dendritic cells (PIDC) pulsed with HPV16 E6 or E7 peptide are capable of eliciting specific immune response in patients with advanced cervical cancer FACS analysis showing the phenotype of PIDCs used in the vaccine preparation. A) After a two day incubation in the presence of GM-CSF, and pulsating with HPV E7 peptide for two hours, CD14 positive cells persistently expressed CD14 at a slightly lower level. B) CD14 positive cells expressed a higher level of CD80 following incubation with GM-CSF and HPV E7 peptide. C) CD14 positive cells expressed a higher level of CD86 following incubation with GM-CSF and HPV E7 peptide. D) CD14 positive cells expressed a higher level of CD1a following incubation with GM-CSF and HPV E7 peptide. E) CD14 positive cells expressed a higher level of the Mannose receptor (CD206) following incubation with GM-CSF and HPV E7 peptide. F) HLA-DR was up-regulated in CD14 positive cells following incubation with GM-CSF and HPV E7 peptide.Back to article page