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Table 1 Luciferase expression does not significantly impact histopathologic characterization of GL261 cells

From: Stable luciferase expression does not alter immunologic or in vivo growth properties of GL261 murine glioma cells

Marker

GL261 N = 5

GL261.luc N = 4

P-value

CD3*

31.3

23.7

0.24

Ki67§

67.3

48.3

0.18

CD31*

31.7

18.3

0.07

  1. *Cells per high power field, §Percentage positive cells.
  2. Analysis of CD3, Ki67, and CD31 in tumor harvested from GL261 and GL261.luc bearing animals. For each marker, six random areas were counted and averaged per tumor specimen.