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Figure 3 | Journal of Translational Medicine

Figure 3

From: Stable luciferase expression does not alter immunologic or in vivo growth properties of GL261 murine glioma cells

Figure 3

Differences in gene expression between GL261 and GL261.luc. Volcano plot (A) demonstrating the differences in gene expression, for 82 cytokine and chemokine genes, between GL261.luc and unmodified GL261 cells. The horizontal grey line indicates the level at which a significance difference (P = 0.05) exists. Points above that line represent genes whose expression is significantly different between the two cells. The vertical grey lines indicate a fold change of 2: either increased or decreased by a factor of 2 in GL261.luc cells. Points outside of the vertical lines represent genes which are more than 2-fold changed. A bar graph (B) depicts the extent of change for the seven genes whose expression is significantly different between GL261.luc and GL261.

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