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Table 2 Accumulation of angiogenic factors in ADSC conditioned media (ng/mln. of cells) measured by ELISA

From: Disturbed angiogenic activity of adipose-derived stromal cells obtained from patients with coronary artery disease and diabetes mellitus type 2

Growth factor Groups of patients
Control CAD CAD + T2DM p-value
VEGF 6,55 (2,9-13,8) 12,3 (5,6-20,3) 7,52 (3,3-19,3) *p = 0,045
HGF 1,19 (0,76-2,2) 3,25 (2,0-5,5) 2,83 (2,12-4,75) *p = 0,021
**p = 0,004
PlGF 0,04 (0,02-0,07) 0,07 (0,03-0,16) 0,24(0,08-0,28) **p = 0,014
Angiogenin 1,62 (0,9-2,9) 1,8 (0,52-2,47) 0,74 (0,56-2,6) NS
Angiopoetin-1 0,47 (0,15-0,9) 0,83 (0,28-1,7) 0,39 (0,18-0,67) NS
PAI-1 40,06 224,17 142,22 *p = 0,0013
(15,5-72,2) (110,2-322,8) (45,0-268,5) **p = 0,0053
THBS-1 169,06 151,99 254,4 NS
(59,7-585,1) (57,3-382,1) (85,1-421,8)
  1. *p-value for CAD group vs. the control group; **p-value for CAD + T2DM group vs. the control group; CAD – Coronary artery disease; T2DM- Diabetes mellitus type 2; NS- Non significant.