Skip to main content

Table 2 Accumulation of angiogenic factors in ADSC conditioned media (ng/mln. of cells) measured by ELISA

From: Disturbed angiogenic activity of adipose-derived stromal cells obtained from patients with coronary artery disease and diabetes mellitus type 2

Growth factor

Groups of patients

Control

CAD

CAD + T2DM

p-value

VEGF

6,55 (2,9-13,8)

12,3 (5,6-20,3)

7,52 (3,3-19,3)

*p = 0,045

HGF

1,19 (0,76-2,2)

3,25 (2,0-5,5)

2,83 (2,12-4,75)

*p = 0,021

**p = 0,004

PlGF

0,04 (0,02-0,07)

0,07 (0,03-0,16)

0,24(0,08-0,28)

**p = 0,014

Angiogenin

1,62 (0,9-2,9)

1,8 (0,52-2,47)

0,74 (0,56-2,6)

NS

Angiopoetin-1

0,47 (0,15-0,9)

0,83 (0,28-1,7)

0,39 (0,18-0,67)

NS

PAI-1

40,06

224,17

142,22

*p = 0,0013

(15,5-72,2)

(110,2-322,8)

(45,0-268,5)

**p = 0,0053

THBS-1

169,06

151,99

254,4

NS

(59,7-585,1)

(57,3-382,1)

(85,1-421,8)

  1. *p-value for CAD group vs. the control group; **p-value for CAD + T2DM group vs. the control group; CAD – Coronary artery disease; T2DM- Diabetes mellitus type 2; NS- Non significant.