Pro-angiogenic growth factor production by ADSC from patients with chronic ischemic pathologies and metabolic disorders was higher compared to the patients of the control group. (A-C) Gene expression of VEGF (A), PlGF (B) and HGF (C) in ADSC obtained from the patients with CAD, CAD + DM2 and the control group. Y-axis: mRNA level in ADSC, relative units. (D-F) Concentration of VEGF (D), PlGF (E) and HGF (F) in ADSC conditioned medium. Y-axis: Protein content in ADSC conditioned medium, ng/mln. of cells. Data are median and percentiles (25-75%), p-values are presented on the graphs.