Figure 6From: Achyranthes bidentata extract exerts osteoprotective effects on steroid-induced osteonecrosis of the femoral head in rats by regulating RANKL/RANK/OPG signaling ABE inhibits osteoclast differentiation in rats with steroid-induced ONFH. (A) Tartrate-resistant acid phosphatase (TRAP) stained sections from the femoral head of control, model, and ABE-treated rats. (B) The number of osteoclasts (multinucleated TRAP-positive cells) in the femoral head of control, model, and ABE-treated rats. (C) Serum TRAP activity in the serum of control, model, and ABE-treated rats. (D) Serum BAP activity in the serum of control, model, and ABE-treated rats. Data are presented as the mean ± S.D. (n =20 for control, n =25 for model, n =20 for ABE 10 g/kg, ABE 15 g/kg, and 22.5 g/kg groups). # and ##: P <0.05 and P <0.01, respectively, in comparison with the control group. * and **: P <0.05 and P <0.01, respectively, in comparison with the model group. The arrow heads indicate osteoclasts.Back to article page