Table 1 Assessment schedule

Week

D0

W4 a 5

W6

W7

W8

W9

W10

W12

W14

W16

W20

W24

BM harvesting

X

MSC expansion, generating

X

Informed consent

X

Medical history

X

X

X

X

X

X

X

X

X

X

X

X

X

Concomitant medication

X

X

X

X

X

X

X

X

X

X

X

X

X

Transplantation information

X

X

X

X

X

X

X

X

X

X

X

X

X

Physical examination

X

X

X

X

X

X

X

X

X

X

X

X

X

Routine lab

X

X

X

X

X

X

X

X

X

X

X

X

X

Viral load CMV and BK

X

X

X

X

X

X

X

X

Urinalysis

X

X

X

X

X

X

X

X

X

X

X

X

X

MSC infusion

X

X

Renal biopsy

X

X

X

Sera for storage

X

X

X

X

X

Iohexol clearance

X

X

Blood for immune monitoring

X

X

X

X

X

X

DSA

X

X#

X

X

Safety assessment

X

X

X

X

X

X

X

X

X

X

X

X

X

Echo cardiography and pulse wave velocity

X

X