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Table 4 Anthropometric and body composition parameters at baseline and after HBD nutritional intervention according to genotypes 1

From: C677T gene polymorphism of MTHFR and metabolic syndrome: response to dietary intervention

Parameters

Baseline

Week 12

Total (n = 44)

T (−) (n = 20)

T (+) (n = 24)

Total (n = 44)

T (−) (n = 20)

T (+) (n = 24)

Weight (Kg)

97.79 ± 15.46

89.60 ± 14.43

103.93 ± 13.69d

88.17 ± 16.01a

80.51 ± 15.00b

93.92 ± 14.78c

BMI (Kg/m 2 )

40.72 ± 5.89

38.58 ± 7.23

42.32 ± 4.31

36.69 ± 6.05a

34.68 ± 7.38

38.20 ± 4.61c

Abdomen (cm)

124.43 ± 12.18

120.06 ± 12.76

127.71 ± 11.12

116.36 ± 12.59a

111.83 ± 12.54b

119.75 ± 12.02c

Hip (cm)

124.24 ± 10.94

119.22 ± 12.58

128.00 ± 8.17

116.55 ± 10.82

111.56 ± 12.09

120.29 ± 8.42c

Neck (cm)

41.93 ± 3.09

39.90 ± 2.88

42.74 ± 2.91

39.23 ± 2.90a

37.88 ± 2.36b

40.51 ± 2.98c

TBFat (Kg)

46.91 ± 8.88

41.03 ± 7.18

51.51 ± 7.57d

40.42 ± 9.36

35.21 ± 7.79b

45.29 ± 8.78c,e

TBLean (Kg)

47.67 ± 8.09

44.86 ± 6.96

50.17 ± 8.95

44.69 ± 7.26a

42.84 ± 6.61

46.33 ± 8.13c

PBF (%)

48.24 ± 3.52

46.50 ± 2.90

49.46 ± 3.56

45.87 ± 3.83a

43.57 ± 3.79

48.01 ± 2.78

BMD total body (g/cm2)

1.21 ± 0.12

1.15 ± 0.11

1.27 ± 0.11

1.19 ± 0.12a

1.14 ± 0.11

1.24 ± 0.11c, e

BMC total body (g)

2460.65 ± 351.30

2270.67 ± 255.15

2645.50 ± 355.62

2507.50 ± 408.15a

2270.67 ± 255.15

2750.60 ± 356.15c

RMR (Kcal/die)

1762.47 ± 299.00

1658.68 ± 257.43

1855.02 ± 330.95

1652.30 ± 268.55

1658.68 ± 257.43

1713.15 ± 300.66c

  1. 1All values are mean ± SD. BMI: Body Mass Index, TBFat: Total Body Fat; TBLean: Total Body Lean; PBF: Percentage of Total Body Fat; BMD: Bone Mineral Density; BMC:Bone Mineral Content; RMR: Resting Metabolic Rate.
  2. aReflects the significance of the differences between total population at baseline vs total population at week 12 determined with an independent t test (p ≤ 0.05).
  3. bReflects the significance of the differences between T(−) carrier at baseline vs T(−) carrier at week 12 determined with an independent t test (p ≤ 0.05).
  4. cReflects the significance of the differences between T(+) carrier at baseline vs T(+) carrier at week 12 determined with an independent t test (p ≤ 0.05).
  5. dReflects the significance of the differences between T(−) carrier at baseline vs T(+) carrier at baseline determined with an independent t test (p ≤ 0.05).
  6. eReflects the significance of the differences between T(−) carrier at week 12 vs T(+) carrier at week 12 determined with an independent t test (p ≤ 0.05).