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Table 4 Anthropometric and body composition parameters at baseline and after HBD nutritional intervention according to genotypes 1

From: C677T gene polymorphism of MTHFR and metabolic syndrome: response to dietary intervention

Parameters Baseline Week 12
Total (n = 44) T (−) (n = 20) T (+) (n = 24) Total (n = 44) T (−) (n = 20) T (+) (n = 24)
Weight (Kg) 97.79 ± 15.46 89.60 ± 14.43 103.93 ± 13.69d 88.17 ± 16.01a 80.51 ± 15.00b 93.92 ± 14.78c
BMI (Kg/m 2 ) 40.72 ± 5.89 38.58 ± 7.23 42.32 ± 4.31 36.69 ± 6.05a 34.68 ± 7.38 38.20 ± 4.61c
Abdomen (cm) 124.43 ± 12.18 120.06 ± 12.76 127.71 ± 11.12 116.36 ± 12.59a 111.83 ± 12.54b 119.75 ± 12.02c
Hip (cm) 124.24 ± 10.94 119.22 ± 12.58 128.00 ± 8.17 116.55 ± 10.82 111.56 ± 12.09 120.29 ± 8.42c
Neck (cm) 41.93 ± 3.09 39.90 ± 2.88 42.74 ± 2.91 39.23 ± 2.90a 37.88 ± 2.36b 40.51 ± 2.98c
TBFat (Kg) 46.91 ± 8.88 41.03 ± 7.18 51.51 ± 7.57d 40.42 ± 9.36 35.21 ± 7.79b 45.29 ± 8.78c,e
TBLean (Kg) 47.67 ± 8.09 44.86 ± 6.96 50.17 ± 8.95 44.69 ± 7.26a 42.84 ± 6.61 46.33 ± 8.13c
PBF (%) 48.24 ± 3.52 46.50 ± 2.90 49.46 ± 3.56 45.87 ± 3.83a 43.57 ± 3.79 48.01 ± 2.78
BMD total body (g/cm2) 1.21 ± 0.12 1.15 ± 0.11 1.27 ± 0.11 1.19 ± 0.12a 1.14 ± 0.11 1.24 ± 0.11c, e
BMC total body (g) 2460.65 ± 351.30 2270.67 ± 255.15 2645.50 ± 355.62 2507.50 ± 408.15a 2270.67 ± 255.15 2750.60 ± 356.15c
RMR (Kcal/die) 1762.47 ± 299.00 1658.68 ± 257.43 1855.02 ± 330.95 1652.30 ± 268.55 1658.68 ± 257.43 1713.15 ± 300.66c
  1. 1All values are mean ± SD. BMI: Body Mass Index, TBFat: Total Body Fat; TBLean: Total Body Lean; PBF: Percentage of Total Body Fat; BMD: Bone Mineral Density; BMC:Bone Mineral Content; RMR: Resting Metabolic Rate.
  2. aReflects the significance of the differences between total population at baseline vs total population at week 12 determined with an independent t test (p ≤ 0.05).
  3. bReflects the significance of the differences between T(−) carrier at baseline vs T(−) carrier at week 12 determined with an independent t test (p ≤ 0.05).
  4. cReflects the significance of the differences between T(+) carrier at baseline vs T(+) carrier at week 12 determined with an independent t test (p ≤ 0.05).
  5. dReflects the significance of the differences between T(−) carrier at baseline vs T(+) carrier at baseline determined with an independent t test (p ≤ 0.05).
  6. eReflects the significance of the differences between T(−) carrier at week 12 vs T(+) carrier at week 12 determined with an independent t test (p ≤ 0.05).