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Table 2 Comparison of clinical parameters of metabolic syndrome at baseline and after HBD nutritional intervention 1

From: C677T gene polymorphism of MTHFR and metabolic syndrome: response to dietary intervention

Parameters Baseline Week 12
Total (n = 44) T (−) (n = 20) T (+) (n = 24) Total (n = 44) T (−) (n = 20) T (+) (n = 24)
Waist (cm) 111.83 ± 11.65 106.06 ± 10.63 116.17 ± 10.80d 103.50 ± 13.07a 97.50 ± 12.74b 108.00 ± 11.87c
SBP (mmHg) 131.67 ± 12.96 135.56 ± 13.33 128.75 ± 12.43 121.05 ± 10.12a 119.67 ± 12.54b 122.08 ± 10.33
DBP (mmHg) 84.33 ± 9.45 84.44 ± 11.30 84.25 ± 8.32 75.48 ± 6.10a 75.56 ± 7.26 75.42 ± 5.42c
Fasting Glucose (mg/dl) 109.68 ± 22.33 115.33 ± 25.72 104.60 ± 18.66d 97.24 ± 7.83 93.57. ± 7.74b 99.80 ± 7.16e
HDL-C (mg/dl) 44.88 ± 11.67 46.59 ± 11.79 43.55 ± 9.58 47.40 ± 15.50 49.15 ± 7.30 46.22 ± 10.78
Triglycerides (mg/dl) 171.11 ± 71.49 164.33 ± 64.31 177.90 ± 79.50d 166.47 ± 64.94 142.62 ± 59.04b 173.57 ± 63.28
  1. 1All values are mean ± SD. SBP: systolic blood pressure; DBP: diastolic blood pressure; HDL-C: HDL cholesterol.
  2. aReflects the significance of the differences between total population at baseline vs total population at week 12 determined with an independent t test (p ≤ 0.05).
  3. bReflects the significance of the differences between T(−) carrier at baseline vs T(−) carrier at week 12 determined with an independent t test (p ≤ 0.05).
  4. cReflects the significance of the differences between T(+) carrier at baseline vs T(+) carrier at week 12 determined with an independent t test (p ≤ 0.05).
  5. dReflects the significance of the differences between T(−) carrier at baseline vs T(+) carrier at baseline determined with an independent t test (p ≤ 0.05).
  6. eReflects the significance of the differences between T(−) carrier at week 12 vs T(+) carrier at week 12 determined with an independent t test (p ≤ 0.05).