FA treatment was without effect against in vivo cardiac LAD ischaemia-reperfusion in fentanyl/propofol-anaesthetised rats. FA treatment during ischaemia did not affect infarction in young, old or Zucker obese animals. (A-F): Area at risk of percentage of left ventricle and infarct size as percentage of area at risk (AAR) for young (A, D), old (B, E) and Zucker obese (C, F) rats; (G-I): Mean arterial pressure (MAP) at baseline and end reperfusion for young (G), old (H) and Zucker obese (I) rats; (J-L): Heart rate (HR) at baseline and end reperfusion for young (J), old (K) and Zucker obese (L) rats. (n = 6-8 animals per group). † P < 0.05 baseline value vs reperfusion value for control group; # P < 0.05 baseline value vs reperfusion value for FA group. Mean ± SEM.