Figure 1

Increased protection against 25 min I and 45 min R with increasing doses of FA in isolated perfused mouse hearts. (A) Cumulative lactate dehydrogenase (LDH) release during 45 min R (index of cell death) in groups treated with different FA doses; (B) End-diastolic pressure (EDP) at end R for the different groups of FA treatment; (C) % Rate-pressure product (RPP) determined at end R and normalized to baseline, pre-ischaemic, values for the different groups. (n = 3 hearts for all groups). Mean ± SEM, * P < 0.05 vs. FA = 0 group.