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Figure 6 | Journal of Translational Medicine

Figure 6

From: Resveratrol ameliorates cardiac dysfunction induced by pressure overload in rats via structural protection and modulation of Ca2+ cycling proteins

Figure 6

Effects of resveratrol on the expressions of proteins responsible for SR Ca 2+ load and sarcoplasmic reticulum Ca 2+ -ATPase activity (n = 3). (A) Representative western blot from each group. (B) The levels of Phospholamban (PLB). (C) The levels of Phospho-PLB (S16) (p-PLB). (D) The ratio of p-PLB to PLB. (E) The levels of Na+/Ca2+-exchangers (NCX 1). (F) The levels of Sarcoplasmic reticulum Ca2+-ATPase (SERCA 2). (G) The ratio of SERCA 2 to PLB. (H) SERCA activity. Levels of proteins were quantified by densitometry and normalized against GADPH. Data are mean ± SEM. * P < 0.05 ** P < 0.01 vs. sham rats; P < 0.05 †† P < 0.01 vs. banded rats.

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