Skip to main content

Advertisement

Table 4 Signaling pathways associated to CLU1 and CLU2 clusters

From: Combined microRNA and ER expression: a new classifier for familial and sporadic breast cancer patients

Signaling pathway P-value Cluster
Regulation of cell death 3.80E-09 CLU1
Cell cycle 7.00E-08 CLU1
ER-nuclear signaling pathway 4.10E-06 CLU1
Angiogenesis 2.00E-04 CLU1
Response to estrogen stimulus 7.30E-04 CLU1
Epithelial to mesenchymal transition 3.40E-03 CLU1
Ras protein signal transduction 9.80E-03 CLU1
Cell motility 1.20E-02 CLU1
Response to hypoxia 1.30E-02 CLU1
Transcription 9.50E-06 CLU2
Regulation of transcription from RNA polymerase II promoter 1.20E-05 CLU2
Transcription repressor activity 1.30E-05 CLU2
Negative regulation of gene expression 3.70E-05 CLU2
Methylation 2.40E-04 CLU2
Histone acetyltransferase activity 1.60E-03 CLU2
Lysine N-acetyltransferase activity 1.60E-03 CLU2