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Table 4 Signaling pathways associated to CLU1 and CLU2 clusters

From: Combined microRNA and ER expression: a new classifier for familial and sporadic breast cancer patients

Signaling pathway

P-value

Cluster

Regulation of cell death

3.80E-09

CLU1

Cell cycle

7.00E-08

CLU1

ER-nuclear signaling pathway

4.10E-06

CLU1

Angiogenesis

2.00E-04

CLU1

Response to estrogen stimulus

7.30E-04

CLU1

Epithelial to mesenchymal transition

3.40E-03

CLU1

Ras protein signal transduction

9.80E-03

CLU1

Cell motility

1.20E-02

CLU1

Response to hypoxia

1.30E-02

CLU1

Transcription

9.50E-06

CLU2

Regulation of transcription from RNA polymerase II promoter

1.20E-05

CLU2

Transcription repressor activity

1.30E-05

CLU2

Negative regulation of gene expression

3.70E-05

CLU2

Methylation

2.40E-04

CLU2

Histone acetyltransferase activity

1.60E-03

CLU2

Lysine N-acetyltransferase activity

1.60E-03

CLU2