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Figure 4 | Journal of Translational Medicine

Figure 4

From: Hepatoprotective and antioxidant activities of extracts from Salvia—Nelumbinis naturalis against nonalcoholic steatohepatitis induced by methionine- and choline-deficient diet in mice

Figure 4

Parameters of oxidative stress of mice. (A) The MDA content of liver was measured. Results are expressed per gram of liver protein extract (n = 8 per group). (B) The hepatic mRNA expression of liver oxidant stress related genes including CYP2E1, Nrf2, Gstp1 and Nqo1 was evaluated by quantitative real-time PCR analysis. Results were normalized to β-actin expression (n = 4 per group). (C) The expression of CYP2E1, JNK and phospho-JNK was evaluated by immunoblot analysis of livers from four mice per group. β-actin was determined as the loading control. Data are expressed as mean ± SD, ***P < 0.001, **P < 0.01, *P < 0.05 vs. control; # P < 0.05 vs. model.

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