| |
SLE
|
Disease controls
| |
|---|
| |
n = 31
|
n = 15
|
p value
|
|---|
|
Intracellular protein levels
| | | |
|
MDA5 (pg/mL)
|
701.53 (543.45,885.96)
|
296.74 (216.50,567.40)
|
<0.01*
|
|
Activated caspase 9
|
9.74 (0.81, 22.34)
|
2.20 (0.26, 3.58)
|
0.06
|
|
Activated caspase 10
|
0.77 (0.51, 2.09)
|
0.15 (0.04, 0.24)
|
<0.01*
|
|
pIRF7
|
0.10 (0.04, 0.30)
|
0.03 (0.01, 0.04)
|
<0.01*
|
|
Activated MAVS
|
0.82 (0.19, 2.59)
|
0.24 (0.11, 0.42)
|
0.02*
|
- Data presented with median, IQR; IQR, inter-quartile range.
- The levels of pIRF7, activated caspase 9, caspase 10, and MAVS from Western blot method were normalized with actin levels.
-
Abbreviation: pIRF7, phosphorylated interferon regulator factor 7; MAVS, mitochondrial anti-viral signaling protein.
- *p < 0.05.
