Figure 2
From: High-throughput profiling identifies clinically actionable mutations in salivary duct carcinoma
Copy number variations in SDC. A. Copy number variations of 37 SDC samples by the NanoSting nCounter Cancer Copy Number Variation Panel. The horizontal axis represents the complete dataset of patients and the vertical axis indicates examined genes. B. ERBB2 gene amplifications were confirmed by FISH analysis, showing clusters of red signals (ERBB2 probe) and 2 green probes (chromosome 17) per nucleus (DAPI staining). C. Disease-free survival (left) and overall survival (right) depicted according to the ERBB2 gene amplification. Patients grouped by strong (copy number ≥10) and moderate (copy number <10) amplification of ERBB2.