A randomised translational trial of lifestyle intervention using a 3-tier shared care approach on pregnancy outcomes in Chinese women with gestational diabetes mellitus but without diabetes

Table 4 Subgroup analysis of predefined pregnancy outcomes of women with gestational diabetes mellitus by assignment

	UC	SC		SC vs. UC	SC vs. UC
Outcomes	Mean (SD) or n(%)	Mean (SD) or n(%)	P value	Unadjusted RR (95% CI)	Adjusted RR^†(95% CI)
Among GDM diagnosed by the IADPSG’s criteria only
n	117	110
Birth weight, g	3522(590)	3454(496)	0.352
Birth weight ≥4.0 kg	25(21.4%)	14(12.7%)	0.085	0.60(0.32-1.09)	0.62(0.34-1.13)
Large for gestational age^†	27(23.1%)	21(19.1%)	0.462	0.83(0.50-1.37)	0.88(0.54-1.46)
Pregnancy-induced hypertension	3(2.6%)	7(6.4%)	0.163	2.48(0.66-9.36)	2.48(0.67-9.26)
Among GDM diagnosed by both IADPSG’s and WHO’s criteria
n	244	229
Birth weight, g	3443(565)	3332(542)	0.030
Birth weight ≥4.0 kg	38(15.6%)	24(10.5%)	0.097	0.67(0.42-1.08)	0.67(0.41-1.09)
Large for gestational age^†	45(18.4%)	23(10.0%)	0.009	0.54(0.34-0.87)	0.52(0.33-0.84)
Pregnancy-induced hypertension	13(5.3%)	20(8.7%)	0.146	1.64(0.84-3.22)	1.56(0.79-3.06)

Abbreviations: SC shared intensive care, UC usual care, IADPSG International Association of Diabetes and Pregnancy Study Group, WHO World Health Organization.
^†Adjusted RR, derived from prevalence ratios that were adjusted for fasting plasma glucose and maternal body height that were marginally significant.
^†Large for gestational age was defined by gender and gestational age specific 90^th percentiles.

ISSN: 1479-5876